Publications#
Machine learning optimization of candidate antibody yields highly diverse sub-nanomolar affinity antibody libraries
Lin Li, Esther Gupta, John Spaeth, Leslie Shing, Rafael Jaimes, Emily Engelhart, Randolph Lopez, Rajmonda S. Caceres, Tristan Bepler and Matthew E. Walsh
Nature Communications 2023
PoET: A generative model of protein families as sequences-of-sequences
Timothy F. Truong Jr, Tristan Bepler
NeurIPS 2023
Learning the protein language: Evolution, structure, and function
Tristan Bepler, Bonnie Berger
Cell Systems 2021
Learning protein sequence embeddings using information from structure
Tristan Bepler, Bonnie Berger
ICLR 2019