Publications#
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Machine learning optimization of candidate antibody yields highly diverse sub-nanomolar affinity antibody libraries
Lin Li, Esther Gupta, John Spaeth, Leslie Shing, Rafael Jaimes, Emily Engelhart, Randolph Lopez, Rajmonda S. Caceres, Tristan Bepler and Matthew E. Walsh
Nature Communications 2023
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PoET: A generative model of protein families as sequences-of-sequences
Timothy F. Truong Jr, Tristan Bepler
NeurIPS 2023
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Learning the protein language: Evolution, structure, and function
Tristan Bepler, Bonnie Berger
Cell Systems 2021
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Learning protein sequence embeddings using information from structure
Tristan Bepler, Bonnie Berger
ICLR 2019